An Innovative Technique for Medical Image Segmentation Using Convolutional Neural Networks Optimized Through Stochastic Gradient Descent
Abstract
Medical image segmentation is crucial due to its essential role in disease therapy. Various challenges such as hair artifacts, illumination variations, and different imaging acquisitions complicate this task. In this paper, we introduce a novel convolutional neural network (CNN) architecture designed to address these challenges. We also compare our method with two well-known architectures, Unet and FCN, to demonstrate the superiority of our approach. Our results, evaluated using four metrics, accuracy, dice coefficient, Jaccard index, and sensitivity show that our method outperforms the other two. We employed Jaccard distance and binary cross-entropy as the loss functions and used SGD+Nesterov as the optimization algorithm, which proved more effective than the Adam optimizer. In the preprocessing step, we included image resizing to speed up the process and image augmentation to enhance the evaluation metrics. As a postprocessing step, we applied a threshold technique to the algorithm's outputs to increase the contrast of the final images. This method was tested on two well-known and publicly available medical image datasets: PH2 for melanoma detection and Chest X-ray images for detecting chest lesions or COVID-19.
Downloads
References
Kim, J.U., H.G. Kim, and Y.M. Ro. Iterative deep convolutional encoder-decoder network for medical image segmentation. in 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). 2017. IEEE.
Chang, Y., et al. Automatic Segmentation and Cardiopathy Classification in Cardiac Mri Images Based on Deep Neural Networks. in 2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP). 2018. IEEE.
Işın, A., C. Direkoğlu, and M. Şah, Review of MRI-based brain tumor image segmentation using deep learning methods. Procedia Computer Science, 2016. 102: p. 317- 324.
Moeskops, P., et al. Deep learning for multi-task medical image segmentation in multiple modalities. in International Conference on Medical Image Computing and Computer- Assisted Intervention. 2016. Springer.
Abdelhafiz, D., et al. Convolutional Neural Network for Automated Mass Segmentation in Mammography. in 2018 IEEE 8th International Conference on Computational Advances in Bio and Medical Sciences (ICCABS). 2018. IEEE.
Fu, H., et al. Retinal vessel segmentation via deep learning network and fully-connected conditional random fields. in 2016 IEEE 13th international symposium on biomedical imaging (ISBI). 2016. IEEE.
Guo, Z., et al., Deep Learning-Based Image Segmentation on Multimodal Medical Imaging. IEEE Transactions on Radiation and Plasma Medical Sciences, 2019. 3(2): p. 162- 169.
M. Emre Celebi, Q. Wen, S. Hwang, H. Iyatomi, and G. Schaefer, “Lesion border detection in dermoscopy images usingensembles of thresholding methods,” Skin Res. Technol., vol. 19, no. 1, pp. e252– e258, 2013.
H. Zhou, X. Li, G. Schaefer, M. E. Celebi, and P. Miller, “Meanshift based gradient vector flow for image segmentation,” Comput.Vis. Image Understand., vol. 117, no. 9, pp. 1004–1016, 2013.
F. Xie and A. C. Bovik, “Automatic segmentation of dermoscopy images using self- generating neural networks seeded by genetic algorithm,” Pattern Recognition, vol. 46, no. 3, pp. 1012–1019, 2013.
Mendonça, T., et al. PH 2-A dermoscopic image database for research and benchmarking. in 2013 35th annual international conference of the IEEE engineering in medicine and biology society (EMBC). 2013. IEEE.
S. Pereira, A. Pinto, V. Alves, and C. A. Silva, “Brain Tumor Segmentation Using Convolutional Neural Networks in MRI Images,” IEEE Trans.Med. Imag., vol. 35, no. 5, pp. 1240–1251, 2016.
Y. LeCun, L. Bottou, Y. Bengio, and P. Haffner, “Gradientbased learning applied to document recognition,” Proceedings of the IEEE, vol. 86, no. 11, pp. 2278–2324, 1998.
S. Ioffe, C. Szegedy, "Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift,11February 2015. [Online].Available:https: //arxiv.org/ abs/1502.0316 7. [Accessed July 2019].
T. Zhang “Solving large scale linear prediction problems using stochastic gradient descent algorithms” - In Proceedings of ICML ‘04.
Y. Yuan, M. Chao, Y.C. Lo, "Automatic Skin Lesion Segmentation Using Deep Fully Convolutional Networks with Jaccard Distance,"IEEE Transactions on Medical Imaging, 2017.
M. H. Jafari, E. Nasr-Esfahani, N. Karimi, S. Soroushmehr, S. Samavi, and K. Najarian, “Extraction of skin lesions from nondermoscopic images using deep learning,” arXiv preprint arXiv:1609.02374, 2016.
M. Avendi, A. Kheradvar, and H. Jafarkhani, “A combined deeplearning and deformable-model approach to fully automatic segmentation of the left ventricle in cardiac MRI,” Med. Image Anal., vol. 30, pp. 108–119, 2016.
T. Mendonça, P. M. Ferreira, J. S. Marques, A. R. Marcal, J. Rozeira, "PH2 - A dermoscopic image database for research and benchmarking," 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 5437 - 5440, 2013.
https: //www.kaggle.com/search?q=Chest+xray+segmentation.
Johnatan Carvalho Souza, Joao Ot ˜ avio Bandeira Diniz, ´ Jonnison Lima Ferreira, Giovanni Lucca Franc¸a da Silva, Aristofanes Corr ´ ea Silva, ˆ Anselmo Cardoso de Paiva, An automatic method for lung segmentation and reconstruction in chest X-Ray using deep neural networks, Computer Methods and Programs in Biomedicine (2019).
D. Gutman, N. C. F. Codella, E. Celebi, B. Helba, M. Marchetti, N. Mishra, A. Halpern, "Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)," 2017. [Online]. Available: https: //challenge.kitware.com/#challenge/583f126bcad3a51cc66c8d9a.
D. Gutman, N. C. F. Codella, E. Celebi, B. Helba, M. Marchetti, N. Mishra, A. Halpern, "Skin Lesion Analysis toward Melanoma Detection: A Challenge at the International Symposium on Biomedical Imaging (ISBI) 2016, hosted by the International Skin Imaging Collaboration (ISIC)," May 2016. [Online]. Available: https ://arxiv.org/abs/1605.01397.